Isolation of Antagonists of Antigen-Specific Autoimmune T Cell Proliferation
نویسندگان
چکیده
منابع مشابه
Isolation of antagonists of antigen-specific autoimmune T cell proliferation.
Antigen-specific T cells play a major role in mediating the pathogenesis of a variety of autoimmune conditions as well as other diseases. In the context of experimental autoimmune encephalomyelitis, a murine model of multiple sclerosis, we present here a general approach to the discovery of highly specific ligands for autoreactive cells. These ligands are obtained from a combinatorial library o...
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ژورنال
عنوان ژورنال: Chemistry & Biology
سال: 2009
ISSN: 1074-5521
DOI: 10.1016/j.chembiol.2009.10.011